Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications

Serial Assessment of Immune Status by Circulating CD8+ Effector T Cell Frequencies for Posttransplant Infectious Complications

Blog Article

To clarify the role of CD8+ effector T cells for infectious complications, 92 recipients were classified according to the hierarchical clustering of preoperative CD8+CD45 isoforms: Group I was naive, Group II was effector memory, and Group III Display Visor was effector (E) T cell-dominant.The posttransplant infection rates progressively increased from 29% in Group I to 64.3% in Group III recipients.The posttransplant immune status was compared with the pretransplant status, based on the measure (% difference) and its graphical Pedal Exercisers form (scatter plot).In Groups I and II, both approaches showed a strong upward deviation from pretransplant status upon posttransplant infection, indicating an enhanced clearance of pathogens.

In Group III, in contrast, both approaches showed a clear downward deviation from preoperative status, indicating deficient cytotoxicity.The % E difference and scatter plot can be used as a useful indicator of a posttransplant infectious complication.